Antibacterial agent 351

Overview

Antibacterial agent 351 is a broad-spectrum antibacterial agent. Antibacterial agent 351 binds to the allosteric site of PBP2a , induces conformational changes, and reduces the level of PBP2a in MRSA. Antibacterial agent 351 acts as a DNA intercalator to interfere with bacterial DNA function. Antibacterial agent 351 disrupts bacterial redox homeostasis via excessive production of ROS and RNS , depletes intracellular GSH , induces lipid peroxidation, and triggers bacterial cell death. Antibacterial agent 351 enhances the activity of Metronidazole ( HY-B0318 ) against anaerobic bacteria and extends the antibacterial spectrum of Metronidazole to aerobic bacteria. Antibacterial agent 351 can be used in the research of bacterial infections (including MRSA infections).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Infection | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Penicillin-binding protein (PBP) | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > DNA Alkylator/Crosslinker

Product Information

• Catalog No.: HY-184284
• CAS No.: 2798832-23-0
• Molecular Formula: C29H28N8O7
• Molecular Weight: 600.58
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source