Anti-inflammatory agent 116

Overview

Anti-inflammatory agent 116 is an anti-inflammatory agent. Anti-inflammatory agent 116 inhibits the abnormal activation of the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 116 binds to the p50 subunit and impairs the DNA-binding ability of the p65 - p50 heterodimer. Anti-inflammatory agent 116 inhibits LPS-induced production of NO and MtROS , secretion of IL-1β and TNF-α , expression of iNOS and COX-2 , phosphorylation of IKK , IκB , p65 , p38 , ERK and JNK , as well as nuclear translocation of p65 . Anti-inflammatory agent 116 alleviates sepsis-associated acute liver injury in mice. Anti-inflammatory agent 116 can be used for the research of sepsis-associated acute liver injury.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Disease | Products > Disease Areas > Liver Injury | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > COX | Products > Signaling Pathways > IKK | Products > Signaling Pathways > ERK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-184324
• CAS No.: 2975573-18-1
• Molecular Formula: C37H55NO5
• Molecular Weight: 593.84
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source