JD-13 is a HPV-1 inhibitor and anti-proliferative agent against cancer cells. JD-13 downregulates the expression of HSV-1 DNA polymerase-related genes UL30 and UL42 , and inhibits viral replication. JD-13 induces apoptosis ( apoptosis ) in colorectal cancer cells and suppresses their colony formation. JD-13 can be applied to the research of herpes simplex virus infection and related diseases including colorectal cancer , lung cancer , esophageal cancer and breast cancer .
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