Energy-coupling factor-IN-1

Overview

Energy-coupling factor-IN-1 is an energy-coupling factor (ECF) transporter inhibitor with an IC 50 of 42.84 μM against ECF-FolT2 . Energy-coupling factor-IN-1 binds to the interface between the S component and the ECF module, and inhibits the uptake of folic acid and pantothenic acid via the target transporter. Energy-coupling factor-IN-1 acts as a bactericidal agent, exerting rapid and sustained activity for 24 h against Enterococcus faecium , while also acting against Gram-positive bacteria including drug-resistant strains. Energy-coupling factor-IN-1 improves the survival rate of zebrafish embryos infected with Enterococcus faecium . Energy-coupling factor-IN-1 can be used in studies of Gram-positive bacterial infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-184417
• CAS No.: 3085883-97-9
• Molecular Formula: C28H29ClN4O5
• Molecular Weight: 537.01
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source