CDK8 ligand 2

Overview

CDK8 ligand 2 is a steroidal CDK8 and CDK19 inhibitor with IC 50 values of 16 nM and 8 nM, respectively. CDK8 ligand 2 shows no activity against NEK1 ( IC 50 >10,000 nM). As a target protein ligand, CDK8 ligand 2 is used for the synthesis of the CDK8 PROTAC degrader ( HY-111518 ).

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Others | Products > Signaling Pathways > Ligands for Target Protein for PROTAC | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-184544
• CAS No.: 2374703-22-5
• Molecular Formula: C30H42N2
• Molecular Weight: 430.67
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source