SPH7854

Overview

SPH7854 is a RORγt inhibitor with human RORγt IC 50 of 10 nM, high selectivity over RORα and RORβ , and oral effectiveness. SPH7854 suppresses RORγt activity, Th17 cell differentiation, and IL-17 production. SPH7854 can be used for the research of inflammatory bowel disease.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Inflammatory Bowel Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR

Product Information

• Catalog No.: HY-184903
• CAS No.: 2796195-48-5
• Molecular Formula: C24H25N3O4S
• Molecular Weight: 451.54
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source