UCP1172

Overview

UCP1172 is an antibacterial ( Antibacterial ) agent and Dihydrofolate reductase inhibitor, with an IC 50 of 0.0089 μM against Staphylococcus aureus DfrB , 0.22 μM against DfrG , 0.41 μM against DfrA , and 0.030 μM against DfrK . UCP1172 potently inhibits the growth of MRSA/MSSA isolates carrying dfrG and dfrK ( MIC values of 0.3125-0.625 μg/mL), shows weak activity against MRSA carrying dfrA ( MIC of 5 μg/mL), and exerts extremely potent inhibitory effects on wild-type S. aureus ATCC 43300 (MIC of 0.0098 μg/mL). UCP1172 can be used in studies related to tuberculosis and Staphylococcus aureus infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Dihydrofolate reductase (DHFR)

Product Information

• Catalog No.: HY-185443
• CAS No.: 1922152-04-2
• Molecular Formula: C24H24N4O3
• Molecular Weight: 416.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source