PROTAC PIN1 degrader-2

Overview

PROTAC PIN1 degrader-2 is a PROTAC PIN1 degrader. PROTAC PIN1 degrader-2 reduces PIN1 -mediated oncogene expression, upregulates PIN1 -inhibited tumor suppressor genes, and exerts killing effects on cancer cells. PROTAC PIN1 degrader-2 inhibits tumor growth in breast cancer mouse xenograft models. PROTAC PIN1 degrader-2 can be used for the research of breast cancer . (Pink: PIN1 ligand ( HY-186219 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > PIN1

Product Information

• Catalog No.: HY-186218
• CAS No.: 3083422-10-7
• Molecular Formula: C28H34ClN3O10S
• Molecular Weight: 640.10
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source