CBP/BRD4-IN-1 (Compound 22) is a dual bromodomain inhibitor of CBP and BRD4 BD1 , with IC 50 values of 1.2 μM and 3.2 μM, respectively. CBP/BRD4-IN-1 serves as a target protein ligand for the synthesis of PROTACs , such as MS8847N1 ( HY-18626 ).
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