(R,R)-Voriconazole ((R,R)-UK-109496) is an enantiomer of Voriconazole ( HY-76200 ). Voriconazole (UK-109496) is a second-generation broad-spectrum triazole antifungal compound that inhibits the biosynthesis of fungal ergosterol. Voriconazole exerts its antifungal activity by inhibiting the 14-α-lanosterol demethylation mediated by fungal cytochrome P450 enzymes . Voriconazole exhibits blood-brain barrier permeability.
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