Fluorescent brightener 71

Overview

Fluorescent brightener 71 (FB71) is an inhibitor targeting deubiquitinases UCHL5 and USP14 , as well as a CD40 ligand. Fluorescent brightener 71 blocks enzymatic activity, induces apoptosis , inhibits cell growth and triggers reactive oxygen species production. Meanwhile, Fluorescent brightener 71 upregulates the expression of oxidative stress-related genes gpx-4 and sod-4 , and reversibly increases the protein levels of UCHL5 and USP14 through a feedback response. Fluorescent brightener 71 inhibits the growth, movement and reproductive capacity of Caenorhabditis elegans , and also exhibits concentration-dependent toxic effects. Fluorescent brightener 71 can be applied to scientific research in related fields such as breast cancer .

Application

Products | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-D1236
• CAS No.: 16090-02-1
• Molecular Formula: C40H38N12Na2O8S2
• Molecular Weight: 924.91
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source