PCL-2 is a reactive oxygen species ( ROS )-responsive fluorescent probe. PCL-2 reacts with ROS to release 6-hydroxy-2-cyanobenzothiazole (HCBT), which then reacts with D-cysteine to form firefly luciferin in situ. PCL-2 must be used in conjunction with IETDC ( HY-D3169 ) to detect the co-existence of hydrogen peroxide and caspase 8 . PCL-2 is applicable to studies related to acute inflammation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Reactive Oxygen Species (ROS)
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