CDg13

Overview

CDg13 is a fluorescent probe that specifically detects living neural stem/progenitor cells. CDg13 localizes to the endoplasmic reticulum via its dihexyl moiety, with no interaction with endoplasmic reticulum biomolecules. CDg13 undergoes selective efflux by active ABCG2 transporters, with increased intracellular accumulation following ABCG2 inhibition or knockdown. CDg13 isolates and enriches self-renewable neural stem/progenitor cells from embryonic mouse brain tissue, stains neural stem/progenitor cells brightly, and sorts ABCG2 low cell populations from heterogeneous populations. (Ex/Em = 520/553 nm)

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > BCRP

Product Information

• Catalog No.: HY-D3179
• CAS No.: 1451048-96-6
• Molecular Formula: C32H35Cl2NO4
• Molecular Weight: 568.53
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source