gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase ( GGT ) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT , and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma.
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