5GluAF-2MeTG

Overview

5GluAF-2MeTG is an activatable fluorescent probe targeting the glutamate carboxypeptidase (CP) activity of PSMA ( Ex/Em =490/500-600 nm). After being hydrolyzed by PSMA , 5GluAF-2MeTG releases a cell membrane-permeable fluorescent product, and achieves fluorescence activation by disrupting donor-excited photoinduced electron transfer (d-PeT). 5GluAF-2MeTG enables fluorescence imaging of live PSMA -expressing prostate cancer cells in vitro and visualizes the carboxypeptidase activity of PSMA . 5GluAF-2MeTG can be used to detect prostate cancer regions in preclinical excised tissue specimens.

Application

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Product Information

• Catalog No.: HY-D3189
• CAS No.: 2370825-44-6
• Molecular Formula: C26H21N3O8
• Molecular Weight: 503.46
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source