CDy11

Overview

CDy11 is a fluorescent probe and amyloid-binding dye ( λ ex =590 nm; λ em =612 nm), with a K a of 29 μM for Pseudomonas aeruginosa Fap . CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa -associated implant and corneal infections.

Application

Products | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Disease Areas > Pseudomonas Aeruginosa Infection | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Infection | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-D3192
• CAS No.: 2028316-07-4
• Molecular Formula: C27H23BF3N3O2
• Molecular Weight: 489.30
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source