DCM-KPV

Overview

DCM-KPV is a fluorescent probe targeting the human intestinal oligopeptide transporter PEPT1/SLC15A1 receptor ( λ ex =480 nm, λ em =620-670 nm). DCM-KPV specifically binds to PepT1 via its KPV domain and mediates receptor-targeted internalization, thus effectively accumulating in the cytoplasm and nucleus of cells overexpressing this receptor. DCM-KPV has the advantages of long emission wavelength, high emission efficiency, low photobleaching, and negligible cytotoxicity. DCM-KPV maintains stable fluorescence intensity under continuous illumination, exhibiting extremely high live cell compatibility. DCM-KPV can specifically accumulate at colonic inflammatory sites through the intestinal mucosa, enabling direct non-invasive visual differentiation between chronic and acute ulcerative colitis groups and the normal group.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Peptic Ulcer Disease | Products > Disease Areas > Ulcerative Colitis | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Fluorescent Dye

Product Information

• Catalog No.: HY-D3210
• CAS No.: 2098632-04-1
• Molecular Formula: C40H48N8O4
• Molecular Weight: 704.86
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source