Casimiroin is a QR2 and Aromatase inhibitor, with an IC 50 of 54.1 μM against QR2 and an IC 50 of 3.92 μM against aromatase. Casimiroin exhibits antimutagenic activity and inhibits DMBA ( HY-W011845 )-induced mutations in Salmonella typhimurium . Casimiroin suppresses DMBA -induced precancerous lesions in mouse mammary organ cultures. Casimiroin can be used in breast cancer-related research.
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