Trichodimerol

Overview

Trichodimerol (BMS-182123) is a TNF-α promoter inhibitor that inhibits the activity of lipopolysaccharide-induced cytokine secretion. Trichodimerol inhibits lipopolysaccharide-induced TNF-α promoter activity, reduces steady-state TNF-α mRNA expression, and does not alter the stability of TNF-α mRNA . Trichodimerol inhibits lipopolysaccharide-induced TNF-α secretion in murine and human immune cells. Trichodimerol reduces lipopolysaccharide-induced IL-1β secretion by 25%-50% in vitro. Trichodimerol does not alter total protein synthesis or constitutive lysozyme secretion at effective concentrations. Trichodimerol can be used for the research of septic shock.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Infection | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-N12104
• CAS No.: 145174-90-9
• Molecular Formula: C28H32O8
• Molecular Weight: 496.55
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source