Hancockiamide C is a phenylacetic piperazine natural products found in Aspergillus hancockii . Hancockiamide C is synthesized via the hkm biosynthetic gene cluster, involving NRPS Hkm11 and the acetyltransferase Hkm3 . Hancockiamide C inhibits seed germination of Arabidopsis thaliana (MIC = 6.3 μg/mL), but shows no activity against Eragrostis tef seeds.
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