Isoeucommin A

Isoeucommin A
  • CAS No.:134859-90-8
  • Formula:C27H34O12
  • M.W.:550.55

Overview

Isoeucommin A is a lignan compound. Isoeucommin A activates the Nrf2 / HO-1 pathway and induces phosphorylation of GSK-3β . Isoeucommin A reduces the levels of pro-inflammatory cytokines TNF-α , IL-1β and IL-6 , decreases the oxidative stress marker MDA , increases the antioxidants SOD and GSH , and alleviates oxidative stress in mesangial cells. Isoeucommin A alleviates renal tissue injury, improves impaired renal function and enhances the viability of renal tubular epithelial cells in diabetic nephropathy models. Isoeucommin A can be used in the research of diabetic nephropathy.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > SOD | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > TNF Receptor

Product Information

  • Catalog No.: HY-N19615
  • CAS No.: 134859-90-8
  • Molecular Formula: C27H34O12
  • Molecular Weight: 550.55
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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