Buddledin A is a 5-LOX inhibitor ( IC 50 = 50.4 μM) and a COX inhibitor ( IC 50 = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Fungal Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > COX
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