MBL-1

Overview

MBL-1 is an orally active anti-inflammatory agent. MBL-1 can be isolated from the fermentation broth of Aspergillus sp. derived from gorgonians. MBL-1 inhibits the activity of the hCOX-2 protein with an IC 50 of 5.77 μM. MBL-1 reduces the production of key pro-inflammatory mediators such as NO , ROS , IL-1β and IL-18 by inhibiting the MAPK/NF-κB and NLRP3 signaling pathways. MBL-1 exerts a protective effect against DSS-induced colitis. MBL-1 can be used for the research of ulcerative colitis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Peptic Ulcer Disease | Products > Disease Areas > Aspergillus Infection | Products > Disease Areas > Ulcerative Colitis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > COX | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-N6189
• CAS No.: 1815632-13-3
• Molecular Formula: C25H26O7
• Molecular Weight: 438.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source