HC102A is an Antibacterial agent and an inhibitor of DosS and DosT histidine sensor kinases, with an IC 50 of 1.9 μM against Mycobacterium tuberculosis DosS . HC102A does not alter the heme redox state of sensor kinases. HC102A reduces triacylglycerol synthesis and accumulation, decreases the survival rate of Mtb under non-replicating persistent and hypoxic conditions, and enhances the sensitivity of Mtb to Isoniazid ( HY-B0329 ). HC102A can be used in research related to tuberculosis.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Bacterial
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.