Wollastonite is a white, chain-structured pyroxene silicate mineral with biocompatibility, biodegradability, osteogenicity and antibacterial properties. Wollastonite induces transient pulmonary inflammatory responses, reversible alveolar macrophage responses, early inflammatory/proliferative mesothelial cell responses, ROS production, and mild chronic pulmonary interstitial inflammation in rats. Wollastonite induces osteogenic differentiation, promotes bone growth, supports angiogenesis, and facilitates the formation of hydroxycarbonate apatite on its surface. Wollastonite enhances the strength, bioactivity and biodegradability of hydroxyapatite scaffolds, and is used to construct porous bone tissue engineering scaffolds. Wollastonite is applied in research related to diseases such as bronchitis, decreased lung function and bone defects.
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