Thalidomide -SH is an E3 ubiquitin ligase cereblon (CRBN) ligand that recruits cereblon protein. Thalidomide -SH is a Thalidomide ( HY-14658 ) derivative. Thalidomide -SH can be linked to a target protein ligand via a linker to form a PROTAC , such as SIAIS056 ( HY-180969 ).
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