DPA-713

Overview

DPA-713 is a blood-brain barrier-permeable, specific translocator protein ( TSPO ) ligand. DPA-713 binds exclusively to TSPO without interacting with central benzodiazepine receptors; its binding can be competitively displaced by excess unlabeled TSPO ligands. After 11 C labeling, DPA-713 enables sensitive quantitative analysis of TSPO expression associated with microglial activation, allowing differentiation between normal and pathological brain tissues. DPA-713 can be used in studies related to neuroinflammation, neurodegenerative diseases, and recently onset schizophrenia.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > CNS Infection | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TSPO | Products > Signaling Pathways > Radionuclide-Drug Conjugates (RDCs)

Product Information

• Catalog No.: HY-W667746
• CAS No.: 386297-97-8
• Molecular Formula: C21H26N4O2
• Molecular Weight: 366.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source