Aculeacin A

Overview

Aculeacin A is a β-1,3-glucan synthase inhibitor. Aculeacin A is an antifungal antibiotic . Aculeacin A inhibits cell wall glucan synthesis in growing yeast cells, induces cell lysis , osmotic fragility, cell aggregation and abnormal cell morphology, without affecting the synthesis of proteins, nucleic acids or mannan. Aculeacin A acts only on growing yeast cells and has a narrow antifungal spectrum, mainly targeting Candida and Torulopsis species. Aculeacin A shows reduced activity in human serum and exhibits a paradoxical dose-response pattern. Aculeacin A has an inoculum effect against some Candida albicans strains, and its activity is pH-stable. Aculeacin A can be used in studies of fungal infections, such as those caused by Candida , Torulopsis and other species.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Candida Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-W747508
• CAS No.: 58814-86-1
• Molecular Formula: C50H81N7O16
• Molecular Weight: 1036.22
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source