CS790AM

Overview

CS790AM (Coppersensor 790 acetoxymethyl ester) is a cell-permeable, Cu + -targeted near-infrared fluorescent probe ( λ abs =760 nm, λ em =790 nm) applicable to live cells. CS790AM can cross lipophilic cell membranes, and is converted into negatively charged CS790 under the action of intracellular esterases to be retained, thus enabling highly sensitive, reversible "turn-on" detection of labile Cu + pools in live cells and mice. CS790AM possesses excellent biocompatibility and selectivity, avoids interference from other metal ions, shows no obvious toxicity, and can be rapidly cleared. CS790AM allows long-term longitudinal monitoring of individual mice, visualizes copper levels in internal organs and isolated livers, and effectively evaluates abnormal copper accumulation in Wilson's disease models (Atp7b -/- ) as well as dynamic changes after chelator treatment. CS790AM can be used for research on Wilson's disease and related copper metabolic disorders.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Fluorescent Dye

Product Information

• Catalog No.: HY-W783351
• CAS No.: 1416808-87-1
• Molecular Formula: C56H70BrN3O9S3
• Molecular Weight: 1105.27
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source