DD04107

Overview

DD04107 is a neuronal exocytosis inhibitor with a rat Syt1-C2B domain binding K a of 2.4 μM. DD04107 interferes with synaptobrevin-syntaxin-SNAP-25 complex formation and Syt1-SNARE complex interaction to block α-calcitonin gene-related peptide ( α-CGRP ) exocytotic release from primary sensory neurons. DD04107 blocks inflammatory ion channel recruitment to nociceptor plasma membranes. DD04107 can be used for the research of chronic inflammatory pain, neuropathic pain, osteosarcoma pain, chemotherapy-induced peripheral neuropathy, diabetic neuropathy, inflammatory pain.

Application

Products | Products > Peptides | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Others | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Others | Products > Signaling Pathways > CGRP Receptor

Product Information

• Catalog No.: HY-182539
• CAS No.: 1202877-06-2
• Molecular Formula: C48H88N14O12S
• Molecular Weight: 1085.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source