Other grades of this product :
| FLURBIPROFEN-D3 Basic information |
| FLURBIPROFEN-D3 Chemical Properties |
| Melting point | 108-110°C | | storage temp. | -20°C Freezer |
| FLURBIPROFEN-D3 Usage And Synthesis |
| Description | Flurbiprofen-d3 is intended for use as an internal standard for the quantification of flurbiprofen (Item Nos. 70250 | 10004207 | 70255) by GC- or LC-MS. Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively). In vivo, flurbiprofen (0.3-4.8 mg/kg, p.o.) reduces carrageenan-induced hind paw edema and yeast-induced fever in rats. Flurbiprofen reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis. It also reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model when administered at a dose of 5 mg/kg. Formulations containing flurbiprofen have been used to manage pain and inflammation associated with arthritis. | | Chemical Properties | White Solid | | Uses | An Isotopically labeled analog of Flurbiprofe | | Uses | An isotopically labelled analog of Flurbiprofen (F598700). |
| FLURBIPROFEN-D3 Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye