4A3-SC10 (10mg/ml solution in methyl acetate)

Overview

4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing 4A3-SC10 and encapsulating an mRNA reporter induce reporter expression in 4T1 breast cancer cells, B16/F10 melanoma cells, and AML12 hepatocytes.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Branched Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Branched Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Multi chargeable lipid | Products > Lipids In Drug Delivery > Branched Lipid > Branched Lipid

Product Information

• Catalog No.: BP-45523
• CAS No.: 1857340-80-7
• Molecular Formula: C83H155N3O16S4
• Molecular Weight: 1579.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source