HD-TAC7 is a potent PROTAC that targets HDAC1, HDAC2, and HDAC3 for degradation. Structurally, it integrates an HDAC-binding ligand and an E3 ligase recruiter, leading to selective modulation of HDAC activity. HD-TAC7 also influences NF-κB p65 levels in macrophages, making it useful for studying inflammatory pathways. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Degraders
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