Pomalidomide-5'-PEG4-Acid

Overview

Pomalidomide-5'-PEG4-Acid is a PROTAC linker featuring a thalidomide, a hydrophilic PEG spacer, and a carboxylic acid. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. The carboxylic acid is reactive towards amines and alcohols with the use of coupling reagents such as EDC or HATU.

Application

PROTAC > PROTAC Linkers > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers | Products > PROTAC, Molecular glue > PROTAC Linkers > Pomalidomide-acid | Products > PROTAC, Molecular glue > PROTAC Linkers > Pomalidomide-acid

Product Information

• Catalog No.: BP-40563
• CAS No.: 2412056-48-3
• Molecular Formula: C24H31N3O10
• Molecular Weight: 521.5
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source