Thalidomide-O-PEG2-Acid (CAS 2488752-64-1) is a synthetic compound used in PROTAC technology for targeted protein degradation. It features a thalidomide-based ligand and a PEG2 linker, facilitating the recruitment of proteins to E3 ubiquitin ligases for proteasomal degradation, enhancing flexibility and spacing in protein targeting applications.
Polyethylene Glycol PEG Linkers > PROTAC Linker > Thalidomide-O-PEG-Acid
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