PROTAC Sirt2 Degrader-1

Overview

PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM). Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-40152
• CAS No.: 2098487-75-1
• Molecular Formula: C40H40N10O8S2
• Molecular Weight: 853
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source