Chloro-PEG2-acid is a PEG linker possessing a chloride group and a terminal carboxylic acid. The hydrophilic PEG chain increases solubility in aqueous media. The chloride (Cl) is a good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Please contact us for GMP-grade inquiries.
PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG Acid | Antibody Drug Conjugates > Amine Reactive > PEG Acid | Drug Delivery, Surface Modification > Amine Reactive > PEG Acid | Products > PEG Linkers > Chloro PEG | Products > PEG Linkers > PEG Acid > Chloro-PEG-CH2CO2H
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