NT1-O12B is a neurotransmitter-derived lipidoid (NT-lipidoid) that enhances brain delivery of BBB-impermeable cargos. When incorporated into lipid nanoparticles (LNPs), it enables BBB crossing and facilitates targeted cargo delivery into neurons for gene silencing or recombination.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > 80-O18 & Analogs
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