PROTAC AR-V7 degrader-1

Overview

PROTAC AR-V7 degrader-1 is a selective degrader targeting the AR-V7 variant, utilizing the VHL E3 ligase to link to the androgen receptor’s DNA binding domain. This orally bioavailable compound demonstrates effective degradation of AR-V7 in relevant cell lines, showcasing its potential in targeting this specific protein interaction. Reagent-grade; for laboratory research purposes only.

Application

Products > PROTAC, Molecular glue > Degraders

Product Information

• Catalog No.: BP-42264
• CAS No.: 2767440-24-2
• Molecular Formula: C41H52N6O6S2
• Molecular Weight: 789
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source