Dithiodipropionic acid can interact with CPUL1 ( HY-151802 ) (a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1 -DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1 , and improves antitumor efficacy against HUH7 cancer cells.
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