Azido-PEG4-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP is a good leaving group when treating with amine-bearing payloads. Azido group will react with DBCO, BCN, or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility.
Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Cit | Products > Click Chemistry Reagents > Azide > Peptide-PEG
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