JNJ-1013 is a selective degrader of IRAK1, featuring a functional group that reduces IRAK1 levels and modulates key signaling molecules like p-IKBα and pSTAT3. It also promotes apoptosis and increases cleaved PARP expression, highlighting its impact on protein regulation and signaling pathways. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Degraders
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