SJ10542 is a selective PROTAC targeting JAK2 and JAK3, employing a phenyl glutarimide (PG) ligand to recruit cereblon (CRBN) for targeted protein degradation. It exhibits strong activity against JAK2 and JAK3, as well as JAK2-fusion proteins. Reagent-grade; for laboratory research purposes only.
Products > PROTAC, Molecular glue > Degraders
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