Lipid TG4C (10mg/ml solution in ethanol)

Overview

Lipid TG4C is an ionizable cationic glycerolipid (pKa = 6.71) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Nebulized administration of LNPs containing lipid TG4C and encapsulating mRNA encoding human hepatocyte growth factor (HGF) reduces bronchoalveolar lavage fluid (BALF) levels of Il-1β, Il-6, and Tnf-α in a mouse model of pulmonary emphysema induced by porcine pancreatic elastase.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > L-369 & Analogs

Product Information

• Catalog No.: BP-45526
• CAS No.: 3028336-07-1
• Molecular Formula: C55H103NO10
• Molecular Weight: 938.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source