SG3199-Val-Ala-PAB

Overview

SG3199-Val-Ala-PAB is a potent (pyrrolobenzodiazepine) PBD dimer prodrug linker-payload featuring a cleavable Val-Ala motif for lysosomal release. Upon activation, SG3199 induces irreversible DNA interstrand crosslinks in the minor groove, making it a key warhead for next-generation ADCs like Tesirine.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Ala-SG3199 | Products > ADC Linker, ADC Payload > ADC Payload > PBD Dimers

Product Information

• Catalog No.: BP-44242
• CAS No.: 1595275-61-8
• Molecular Formula: C49H59N7O11
• Molecular Weight: 922.1
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source