I-BRD9

Overview

I-BRD9 is a selective cellular chemical probe for bromodomain-containing protein 9 (BRD9). I-BRD9 has a pIC50 value of 7.3 for BRD9 inhibitor, with greater than 700-fold selectivity over the BET family and 200-fold over the highly homologous bromodomain-containing protein 7 (BRD7). I-BRD9 is also shows a greater than 70-fold selectivity against a panel of 34 bromodomains. I-BRD9 downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi-1 cells. Please contact us for GMP-grade inquiries.

Application

Products > PROTAC, Molecular glue > Inhibitors

Product Information

• Catalog No.: BP-25356
• CAS No.: 1714146-59-4
• Molecular Formula: C22H22F3N3O3S2
• Molecular Weight: 497.6
• Storage: -20°C
• Availability: In Stock

Source

Original product source