Bempedoic acid is a prodrug converted to ETC-1002-CoA, which inhibits ATP citrate lyase and activates AMP-activated protein kinase (AMPK). It suppresses lipid synthesis in hepatocytes and reduces hepatic cholesterol and aortic atherosclerotic lesions in mice on a high-fat diet.
Products > PROTAC, Molecular glue > Aliphatic Linkers | Products > PROTAC, Molecular glue > Aliphatic Linkers > Bis-aliphatic-acid
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