Lurtotecan, a semi-synthetic analog of camptothecin, stabilizes the topoisomerase I-DNA complex, inhibiting DNA replication and causing apoptosis through the formation of an enzyme-drug-DNA ternary complex. It also disrupts RNA synthesis, promotes the degradation of topoisomerase I, and alters chromatin structure, making it useful in PROTAC development for targeted cancer treatments.
Products > ADC Linker, ADC Payload > ADC Payload | Products > ADC Linker, ADC Payload > ADC Payload > Lurtotecan
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.
日本语
한국어
Français
Deutsch
España
Türkiye