3,4-Dibromo-Mal-PEG4-Acid

Overview

3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. Dibromo-Maleimide is sensitive to high temperature and light. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.

Application

PEGylation of Protein, Peptide & Oligo > Thiol Reactive > Maleimide Linkers | Antibody Drug Conjugates > Thiol Reactive > Maleimide Linkers | Drug Delivery, Surface Modification > Thiol Reactive > Maleimide Linkers | Products > PEG Linkers > Maleimide Linkers | Products > ADC Linker, ADC Payload > Site Specific Linkers > 3,4-Dibromo-Mal-PEG-Acid | Products > PEG Linkers > Maleimide Linkers > 3,4-Dibromo-Mal-PEG-Acid

Product Information

• Catalog No.: BP-28207
• CAS No.: 2434639-17-3
• Molecular Formula: C15H21Br2NO8
• Molecular Weight: 503.1
• Storage: -20°C
• Solubility: Water, DMSO, DMF, DCM
• Availability: In Stock

Source

Original product source