Lipid I97 (10mg/ml solution in methyl acetate)

Overview

Lipid I97 is a vitamin B5-derived ionizable cationic lipid (pKa = 6.23) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing lipid I97 and encapsulating luciferase mRNA selectively accumulate in the spleen and lymph nodes in mice. LNPs containing lipid I97 and encapsulating mRNA encoding hemagglutinin A induce IgG1 and IgG2 production in mice.

Application

PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Lipid I97 & Analogs

Product Information

• Catalog No.: BP-45535
• CAS No.: 3046404-81-0
• Molecular Formula: C55H102N2O11
• Molecular Weight: 967.4
• Storage: -20°C
• Availability: 24 Hours

Source

Original product source